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产品信息
A30974
产品规格
种属
Human
Expression System
Insect cells
氨基酸序列
Full length
标签
GST-tag
分子量
105.9 kDa
分类
Recombinant
类型
Protein
偶联物
形式
Liquid
浓度
See Label
纯化类型
purified
保存液
50mM tris HCl, pH 7.5, with 10mM glutathione, 150mM NaCl, 0.1mM PMSF, 25% glycerol, 0.1mM EDTA, 0.25mM DTT
内含物
no preservative
保存条件
-80° C, Avoid Freeze/Thaw Cycles
运输条件
Dry ice
产品详细信息
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
This HUNK recombinant human protein (full length) was expressed in insect cells.
HUNK recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the LanthaScreen™ Eu Kinase Binding assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service
Protein Form: Full Length, Recombinant, Active
The gene accession number for HUNK is NP_055401.1.
靶标信息
HUNK serine/threonine kinase or hormonally up-regulated Neu-associated kinase is a member of the mitogen-activated protein kinase family which is essential for mammary tumor metastasis. HUNK deletion in mice did not alter viability, fertility, longevity, or propensity to develop tumors and it is also dispensable for murine development. HUNK has been shown to participate in vesicular transport. Additionally, functional studies in mice suggest that HUNK regulates endocytosis via interaction with rabaptin-5 protein and induces changes in mammary glands during pregnancy. HUNK expression has been documented in mouse brain, breast, embryo, and fetus. ESTs have been isolated from several human tissue libraries, including normal ear.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B19; Hormonally up-regulated neu tumor-associated kinase; hormonally upregulated neu tumor-associated kinase; hormonally upregulated Neu-associated kinase; serine/threonine protein kinase MAK-V; Serine/threonine-protein kinase MAK-V
基因别名: HUNK; MAKV
UniProt ID: (Human) P57058
Entrez Gene ID: (Human) 30811
