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Highest antigen sequence indentity to the following orthologs: Mouse (99%), Rat (99%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51719. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
SUFU encodes a component of the Sonic hedgehog (SHH; MIM 600725)/Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ARF-binding protein 1; ARF-BP1; BJ-HCC-24 tumor antigen; E3 ubiquitin-protein ligase HUWE1; HECT domain protein LASU1; HECT, UBA and WWE domain-containing protein 1; HECT-type E3 ubiquitin transferase HUWE1; HectH9; Homologous to E6AP carboxyl terminus homologous protein 9; Large structure of UREB1; LASU1; Mcl-1 ubiquitin ligase E3; Mule; RP3-339A18.4; Upstream regulatory element-binding protein 1; URE-B1; URE-binding protein 1
基因别名: ARF-BP1; HECTH9; HSPC272; HUWE1; Ib772; KIAA0312; KIAA1578; LASU1; MULE; URE-B1; UREB1
UniProt ID: (Human) Q7Z6Z7
Entrez Gene ID: (Human) 10075