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Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
HHEX is a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation. Establishes anterior identity at two levels 1) acts early to enhance canonical WNT-signaling by repressing expression of TLE4 and 2) acts later to inhibit NODAL-signaling by directly targeting NODAL.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Hematopoietically-expressed homeobox protein HHEX; homeobox; Homeobox protein HEX; Homeobox protein PRH; homeobox, hematopoietically expressed; Proline-rich homeodomain protein; proline-rich homeodomain-containing transcription factor
基因别名: HEX; HHEX; HMPH; HOX11L-PEN; PRH; PRHX
UniProt ID: (Human) Q03014
Entrez Gene ID: (Human) 3087