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Highest antigen sequence indentity to the following orthologs: Mouse (73%), Rat (73%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-145150. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 39S ribosomal protein L58, mitochondrial; Digestion substraction 1; DS-1; Immature colon carcinoma transcript 1 protein; Large ribosomal subunit protein mL62; MRP-L58; Peptidyl-tRNA hydrolase ICT1, mitochondrial
基因别名: DS-1; DS1; ICT1; MRP-L58; MRPL58
UniProt ID: (Human) Q14197
Entrez Gene ID: (Human) 3396