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产品信息
PHC9614
应用
建议稀释比
已发表文章
产品规格
种属
Human
Expression System
HEK293 cells
标签
His-tag
分子量
26 kDa
分类
Recombinant
类型
Protein
纯度
≥95% by SDS-PAGE
内毒素浓度
<1 EU/µg
活性
ED50 ≤ 0.2 µg/mL; determined by the dose-dependent inhibition of MCF-7 cell proliferation in the presence of IGF2 (14 ng/mL).
偶联物
形式
Lyophilized
纯化类型
purified
内含物
no preservative
保存条件
4° C
运输条件
Wet ice
产品详细信息
Carrier-Free
Reconstitution: We recommend that the vial be briefly centrifuged to bring the contents to the bottom prior to opening. Lyophilized recombinant human IGFBP-4 should be reconstituted in sterile PBS to 0.1-1.0 mg/mL to regain full activity. These stock solutions should be apportioned into working aliquots and stored at -20°C. Further dilutions should be made in medium or buffered solution containing carrier protein, such as PBS with 0.1% BSA.
Storage: Lyophilized human IGFBP-4 should be stored at 2-8°C, preferably desiccated. Store reconstituted human IGFBP-4 at -20°C (not in a frost-free freezer). Keep freeze-thaw cycles to a minimum.
靶标信息
This gene is a member of the insulin-like growth factor binding protein family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: IBP-4; IGF-binding protein 4; IGFBP; Insulin like growth factor binding protein; insulin-like growth factor binding protein 4; Insulin-like growth factor-binding protein 4
基因别名: BP-4; HT29-IGFBP; IBP4; IGFBP-4; IGFBP4
UniProt ID: (Human) P22692
Entrez Gene ID: (Human) 3487
