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Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51693. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: angiomodulin; IBP-7; IBP7; IGF-binding protein 7; IGFBP; IGFBP rP1; IGFBP-rP1; Insulin like growth factor binding protein; insulin-like growth factor binding protein 7; Insulin-like growth factor-binding protein 7; MAC25 protein; PGI2-stimulating factor; Prostacyclin-stimulating factor; TAF; Tumor-derived adhesion factor
基因别名: AGM; FSTL2; IBP-7; IGFBP-7; IGFBP-7v; IGFBP7; IGFBPRP1; MAC25; PSF; RAMSVPS; TAF
UniProt ID: (Human) Q16270
Entrez Gene ID: (Human) 3490