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Highest antigen sequence indentity to the following orthologs: Mouse (49%), Rat (49%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63426. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: IgSF5; immunoglobulin superfamily 5 like; Immunoglobulin superfamily member 5; immunoglobulin superfamily, member 5; JAM-4; Junctional adhesion molecule 4
基因别名: GSF5; IGSF5; JAM4
UniProt ID: (Human) Q9NSI5
Entrez Gene ID: (Human) 150084