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Highest antigen sequence indentity to the following orthologs: Mouse (67%), Rat (67%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84592. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Human Interleukin 9 (IL9) was first identified based on its proliferative activity on a human myeloid leukemic cell line. Human IL9 stimulates the proliferation of the human megakaryocytic leukemic cell line M07e. Human IL9 supports erythroid colony formation and synergizes with IL4 in the production of IgE and IgG. The interleukin 9 receptor is a member of the hematopoietin receptor superfamily. The cDNAs encoding mouse and human IL9 receptors have been isolated. The deduced mouse and human transmembrane proteins, sharing 53% amino acid sequence identity, contain 468 and 533 amino acid residues, respectively. A number of isoforms of IL9R, including a putative soluble form, have also been identified. The IL9 receptor is expressed in a variety of hematopoietic cells including T cells, neutrophils, mast cells, and macrophages.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD129; IL-9 receptor; Interleukin-9 receptor
基因别名: CD129; IL-9R; IL9R
UniProt ID: (Human) Q01113
Entrez Gene ID: (Human) 3581