Search Thermo Fisher Scientific
Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51447. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HBEAG-binding protein 2 binding protein C; HBEBP2-binding protein C; inverted formin; inverted formin 2; Inverted formin-2; MGC13251
基因别名: C14orf151; C14orf173; CMTDIE; FSGS5; INF2; pp9484
UniProt ID: (Human) Q27J81
Entrez Gene ID: (Human) 64423