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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the "Signalosome", which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 38 kDa Mov34 homolog; COP9 constitutive photomorphogenic homolog subunit 5; COP9 signalosome complex subunit 5; Jun activation domain-binding protein 1; MGC3149; SGN5; signalosome subunit 5; testis secretory sperm-binding protein Li 231m
基因别名: COPS5; CSN5; JAB1; MOV-34; SGN5
UniProt ID: (Human) Q92905
Entrez Gene ID: (Human) 10987