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Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65220. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Kin is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by the human ortholog.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Binding to curved DNA; DNA/RNA-binding protein KIN17; KIN, antigenic determinant of recA protein homolog
基因别名: BTCD; KIN; KIN17; Rts2
UniProt ID: (Human) O60870
Entrez Gene ID: (Human) 22944