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Highest antigen sequence indentity to the following orthologs: Mouse (73%), Rat (73%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111465. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Krueppel-like factor 11; Kruppel-like factor 11; TGFB-inducible early growth response protein 2; TIEG-2; Transforming growth factor-beta-inducible early growth response protein 2
基因别名: FKLF; FKLF1; KLF11; MODY7; TIEG2; Tieg3
UniProt ID: (Human) O14901
Entrez Gene ID: (Human) 8462