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产品信息
RP-108927
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
ERLVTEKASVYCVAAVLWTAAKFSVPRNHKLALPRRLKTLLLDMARRSAPERPSAAEAIKVCGSYLLQRGMDSRKILAHLRASICQVYQ
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-139829. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The protein encoded by this gene is a Ras guanine nucleotide exchange factor that appears to negatively regulate dendritic growth in the brain. Knockdown of this gene in senescent umbilical vein endothelial cells partially reversed the senescence, showing that this gene could potentially be targeted by anti-aging therapies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cerebral protein 9; kinase non-catalytic C-lobe domain (KIND) containing 1; Kinase non-catalytic C-lobe domain-containing protein 1; kind; KIND domain-containing protein 1; Protein very KIND; Ras-GEF domain-containing family member 2; RasGEF domain family, member 2; v-KIND
基因别名: bB439H18.3; C10orf23; hucep-9; KIAA1768; KNDC1; RASGEF2; VKIND
UniProt ID: (Human) Q76NI1
Entrez Gene ID: (Human) 85442
