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This peptide corresponds to 15 amino acids near the amino terminus of human KPNA4.
PEP-1147 can be used as a blocking peptide with polyclonal antibody PA5-21033.
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
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蛋白别名: Importin alpha Q1; Importin subunit alpha-3; importin subunit alpha-4; importin-alpha-Q1; karyopherin alpha 4; karyopherin alpha 4 (importin alpha 3); Karyopherin subunit alpha-4; MGC12217; MGC26703; Qip1; Qip1 protein
基因别名: IPOA3; KPNA4; QIP1; SRP3
UniProt ID: (Human) O00629
Entrez Gene ID: (Human) 3840