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Highest antigen sequence indentity to the following orthologs: Mouse (76%), Rat (76%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57388. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: H NRPN; hK8; Kallikrein-8; kallikrein-related peptidase 8; Kallikrein8; Neuropsin; NP; Ovasin; PRO322; Serine protease 19; Serine protease TADG-14; Tumor-associated differentially expressed gene 14 protein; UNQ283
基因别名: HNP; KLK8; NP; NRPN; PRSS19; TADG14; UNQ283/PRO322
UniProt ID: (Human) O60259
Entrez Gene ID: (Human) 11202