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Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-64236. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 4-1BB-mediated signaling molecule; 4-1BB-mediated-signaling molecule; 4-1BBlrr; cyclophilin-like 5; Leucine-rich repeat protein 1; LRR-1; LRR-repeat protein 1; peptidylprolyl isomerase (cyclophilin)-like 5, isoform 3; Peptidylprolyl isomerase-like 5
基因别名: 4-1BBLRR; LRR-1; LRR1; PPIL5
UniProt ID: (Human) Q96L50
Entrez Gene ID: (Human) 122769