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产品信息
RP-100074
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
PEVCTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRA
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (67%), Rat (67%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63285. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The LRRC26 protein was initially identified as a cytokeratin-associated protein whose expression was elevated in multiple cancer cell lines and cancer specimens as well in normal prostate and salivary gland tissues. LRRC26 was later found to negatively regulate the NF-kappaB activation and suppresses tumor growth and metastasis. LRRC26 can also act to selectively alter the efficacy of large conductance calcium-activated K (BK) channels.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BK channel auxiliary gamma subunit LRRC26; BK channel auxilliary gamma subunit LRRC26; cytokeratin associated protein; Cytokeratin-associated protein in cancer; Leucine-rich repeat-containing protein 26
基因别名: bA350O14.10; CAPC; LRRC26
UniProt ID: (Human) Q2I0M4
Entrez Gene ID: (Human) 389816
