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产品信息
RP-89772
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
KDREQRGQENTSGFWLNRSNELIWLELQAWHAGRTINDQDFFLYTARQAIPDIINEILTFKVDYGSFAFVRDRAGFNGTSVEGQCKATPGTKIVGYSTHHEHLQRQRVSFEQVKRIMELLEYIEALYPSLQ
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52459. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4); JNKK1; MAP three kinase 1; MAP/ERK kinase kinase 4; MAP2K4; MAPK/ERK kinase kinase 4; MEK kinase 4; Mitogen-activated protein kinase kinase kinase 4; predicted protein of HQ0412; PRKMK4; SAPK/ERK kinase 1; SERK1; SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of
基因别名: KIAA0213; MAP3K4; MAPKKK4; MEKK 4; MEKK4; MTK1; PRO0412
UniProt ID: (Human) Q9Y6R4
Entrez Gene ID: (Human) 4216
