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Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52775. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
MRAP encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: B27; Fat cell-specific low molecular weight protein; Fat tissue-specific low MW protein; Melanocortin-2 receptor accessory protein
基因别名: B27; C21orf61; FALP; FGD2; GCCD2; MRAP
UniProt ID: (Human) Q8TCY5
Entrez Gene ID: (Human) 56246