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Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82642. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. May play an important role in the pathogenesis of neurogenetic diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Brain-expressed X-linked protein 3; nerve growth factor receptor (TNFRSF16) associated protein 1; Nerve growth factor receptor-associated protein 1; Ovarian granulosa cell 13.0 kDa protein HGR74; p75NTR-associated cell death executor; Protein BEX3; RP13-349O20.1
基因别名: Bex; BEX3; DXS6984E; HGR74; NADE; NGFRAP1
UniProt ID: (Human) Q00994
Entrez Gene ID: (Human) 27018