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Highest antigen sequence indentity to the following orthologs: Mouse (25%), Rat (25%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63859. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP13 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP13, it has been suggested that it may be implicated in the activation of proinflammatory caspases via inflammasomes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: NACHT, leucine rich repeat and PYD containing 13; NACHT, LRR and PYD containing protein 13; NACHT, LRR and PYD domains-containing protein 13; NLR family, pyrin domain containing 13; Nucleotide-binding oligomerization domain protein 14; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13
基因别名: CLR19.7; NALP13; NLRP13; NOD14; PAN13
UniProt ID: (Human) Q86W25
Entrez Gene ID: (Human) 126204