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产品信息
RP-108172
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
SGCLELTDSCQPYRSAFYVLEQQRV
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (40%), Rat (40%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83644. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
NBPF15 (NBPF Member 15), located on 1q21.1, is a Protein Coding gene. This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family contains numerous pseudogenes. Human NBPF15 encodes a 670 AA protein consisting of six clades of Olduvai domains. The entanglements between the mosaic disorder-ordered segments in the NBPF15 N terminus have triggered the multiple types of aggregates and phase transition of NBPF15 proteins, which could be associated with Olduvai-related cognitive dysfunction diseases. Diseases associated with NBPF15 include Neuroblastoma and Hydrolethalus Syndrome 1. An important paralog of this gene is NBPF14.
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生物信息学
蛋白别名: AB14; NBPF; NBPF Member 15; Neuroblastoma breakpoint family member 15; Neuroblastoma breakpoint family member 16; Neuroblastoma Breakpoint Family, Member 1; neuroblastoma breakpoint family, member 15; Neuroblastoma Breakpoint Family, Member 16
基因别名: AB14; AG3; NBPF15; NBPF16
UniProt ID: (Human) Q8N660
Entrez Gene ID: (Human) 284565
