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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54741. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a magnesium transporter that associates with early endosomes and the cell surface in a variety of neuronal and epithelial cells. This protein may play a role in nervous system development and maintenance. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with autosomal dominant spastic paraplegia 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Magnesium transporter NIPA1; non-imprinted in Prader-Willi/Angelman syndrome 1; Non-imprinted in Prader-Willi/Angelman syndrome region protein 1; Spastic paraplegia 6 protein
基因别名: FSP3; NIPA1; SPG6
UniProt ID: (Human) Q7RTP0
Entrez Gene ID: (Human) 123606