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Highest antigen sequence indentity to the following orthologs: Mouse (37%), Rat (37%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66729. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
NPW is processed into 23- and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade. The preproprotein is translated using a non-AUG initiation codon that is inferred from analyses of the mouse ortholog.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hPPL8; Neuropeptide W; PP PPNPW; prepro-neuropeptide W; Preproprotein L8
基因别名: L8; L8C; NPW; PPL8; PPNPW
UniProt ID: (Human) Q8N729
Entrez Gene ID: (Human) 283869