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Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63774. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 133 kDa nucleoporin; Nuclear pore complex protein Nup133; nucleoporin 133kD; nucleoporin 133kDa; Nucleoporin Nup133
基因别名: hNUP133; NUP133
UniProt ID: (Human) Q8WUM0
Entrez Gene ID: (Human) 55746