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Highest antigen sequence indentity to the following orthologs: Mouse (75%), Rat (75%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61979. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for processing of TGFA and for targeting of TGFA to the basolateral membrane of polarized epithelial cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dvl-binding protein NKD2; hNkd2; naked cuticle-2; Naked-2; Protein naked cuticle homolog 2
基因别名: Naked2; NKD2
UniProt ID: (Human) Q969F2
Entrez Gene ID: (Human) 85409