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Highest antigen sequence indentity to the following orthologs: Mouse (79%), Rat (79%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63067. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
OMA1 (Overlapping with the m-AAA protease 1 homolog) is also named as MPRP1(Metalloprotease-related protein 1) and belongs to the peptidase M48 family. It is a zinc metalloprotease that spans the inner mitochondrial membrane with a number of predicted membrane spanning domains and the 60 kDa form of OMA1 rapidly accumulated concomitantly with the cleavage of all OPA1 variants, and the 40 kDa form of OMA1 may be the inactive form, with the 60 kDa form being the active enzyme.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Metalloendopeptidase OMA1, mitochondrial; metalloprotease related protein 1; Metalloprotease-related protein 1; MPRP-1; OMA1 homolog, zinc metallopeptidase; OMA1 zinc metallopeptidase homolog; overlapping activity with M-AAA protease; Overlapping with the m-AAA protease 1 homolog; zinc metallopeptidase OMA1
基因别名: 2010001O09Rik; DAB1; MPRP-1; MPRP1; OMA1; peptidase; YKR087C; ZMPOMA1
UniProt ID: (Human) Q96E52
Entrez Gene ID: (Human) 115209