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Highest antigen sequence indentity to the following orthologs: Mouse (59%), Rat (59%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60855. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ22187; FLJ25932; MGC75494; Optic atrophy 3 (Iraqi-Jewish 'optic atrophy plus'); Optic atrophy 3 protein
基因别名: MGA3; OPA3
UniProt ID: (Human) Q9H6K4
Entrez Gene ID: (Human) 80207