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Highest antigen sequence indentity to the following orthologs: Mouse (74%), Rat (74%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62248. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a member of the GDSL/SGNH superfamily. Members of this family are hydrolytic enzymes with esterase and lipase activity and broad substrate specificity. This protein belongs to the Pmr5-Cas1p-esterase subfamily in that it contains the catalytic triad comprised of serine, aspartate and histidine and lacks two conserved regions (glycine after strand S2 and GxND motif). A pseudogene of this gene has been identified on the long arm of chromosome 2. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: f113a; family with sequence similarity 113, member A; PC-esterase domain-containing protein 1A; Protein FAM113A; Sarcoma antigen NY-SAR-23
基因别名: bA12M19.1; C20orf81; FAM113A; PCED1A
UniProt ID: (Human) Q9H1Q7
Entrez Gene ID: (Human) 64773