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产品信息
PHG0134
应用
建议稀释比
已发表文章
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
Human PDGF-AB recombinant protein is a disulfide-linked heterodimer containing one 125 amino acid alpha chain and one 109 amino acid beta chain
分子量
25.5 kDa
分类
Recombinant
类型
Protein
纯度
≥98% by SDS-PAGE
内毒素浓度
<0.1 ng/µg
活性
ED50 ≤ 1.0 ng/mL; determined by the dose-dependent stimulation of thymidine uptake by Balb/c 3T3 cells.
偶联物
形式
Lyophilized
纯化类型
purified
内含物
no preservative
保存条件
-20°C
运输条件
Wet ice (domestic); Wet or Dry ice (international)
产品详细信息
Carrier-Free
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in 10 mM acetic acid to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2°C to 8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein, such as 0.1% BSA and store in working aliquots at -20°C to -80°C.
Storage: The lyophilized protein is stable at room temperature for 1 month, but should be kept at -20°C for long term storage, preferably desiccated. Working aliquots stored with a carrier protein are stable for at least 12 months at -20°C to -80°C. Avoid repeated freeze/thaw cycles.
靶标信息
Platelet-Derived Growth Factor (PDGF) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets and is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. The synthesis of PDGF can be induced by IL-1, IL-6, TNF-alpha, TGF-beta and EGF.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: becaplermin; H-PDGF-AB; PDGF A-chain; PDGF subunit A; PDGF subunit B; PDGF, B chain; PDGF-1; PDGF-2; PDGFAB; platelet-derived growth factor 2; Platelet-derived growth factor A chain; platelet-derived growth factor A-chain; platelet-derived growth factor alpha chain; Platelet-derived growth factor alpha polypeptide; Platelet-derived growth factor B chain; Platelet-derived growth factor beta polypeptide; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog); Platelet-derived growth factor subunit A; Platelet-derived growth factor subunit B; platelet-derived growth factor, beta polypeptide (oncogene SIS); Proto-oncogene c-Sis
基因别名: c-sis; IBGC5; PDGF-2; PDGF-A; PDGF1; PDGF2; PDGFA; PDGFB; SIS; SSV
UniProt ID: (Human) P04085, (Human) P01127
Entrez Gene ID: (Human) 5154, (Human) 5155
