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Highest antigen sequence indentity to the following orthologs: Mouse (55%), Rat (55%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-140211. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: intestinal and kidney enriched PDZ protein; Intestinal and kidney-enriched PDZ protein; Na(+)/H(+) exchange regulatory cofactor NHE-RF4; Na/Pi cotransporter C-terminal-associated protein 2; naPi-Cap2; Natrium-phosphate cotransporter IIa C-terminal-associated protein 2; NHERF-4; PDZ domain containing 2; PDZ domain-containing protein 2; PDZ domain-containing protein 3; Sodium-hydrogen exchanger regulatory factor 4
基因别名: DLNB27; IKEPP; NHERF4; PDZD3; PDZK2
UniProt ID: (Human) Q86UT5
Entrez Gene ID: (Human) 79849