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Highest antigen sequence indentity to the following orthologs: Mouse (79%), Rat (79%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65682. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is associated with the nuclear scaffold in proliferating cells. It was found to bind to the catalytic subunit of protein phosphatase-1 (PP1) and inhibit PP1 activity, suggesting that this protein may function as a regulatory subunit of PP1. Alternative splicing at this locus results in several transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Phosphatase and actin regulator 3; protein phosphatase 1, regulatory subunit 123; Scaffold-associated PP1-inhibiting protein; Scapinin
基因别名: C20orf101; H17739; PHACTR3; PPP1R123; SCAPIN1; SCAPININ
UniProt ID: (Human) Q96KR7
Entrez Gene ID: (Human) 116154