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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51462. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp element and together with parts of RPB1 and RPB2 forms a pocket to which the RPB4-RPB7 subcomplex binds.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DNA-directed RNA polymerase II subunit F; DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide; DNA-directed RNA polymerases I, II, and III subunit RPABC2; hsRPB6; polymerase (RNA) II (DNA directed) polypeptide F; polymerase (RNA) II subunit F; RNA Polymerase II subunit 14.4 kD; RNA polymerases I, II, and III subunit ABC2; RPABC14.4; RPB14.4; RPB6 homolog; RPC15
基因别名: HRBP14.4; POLR2F; POLRF; RPABC14.4; RPABC2; RPB14.4; RPB6; RPC15
UniProt ID: (Human) P61218
Entrez Gene ID: (Human) 5435