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Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60420. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The PPFIA3 protein is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family, a family of transmembrane protein tyrosine phosphatases known to be important for axon guidance and mammary gland development. Similar to the other liprin family members, PPFIA3 can interact with ERC2, a member of the ELKS-Rab6-interacting protein-CAST family of proteins at the presynaptic termini, suggesting that these proteins may play a role in the molecular organization of presynaptic zones.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: liprin; liprin-alpha 3; Liprin-alpha-3; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3; protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3; protein tyrosine phosphatase, receptor type, f polypeptide, alpha 3; PTPRF-interacting protein alpha-3
基因别名: KIAA0654; LPNA3; PPFIA3
UniProt ID: (Human) O75145
Entrez Gene ID: (Human) 8541