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产品信息
RP-91580
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
TVIVVFLRDMNKAVNVSEESDWTENSFQGGQEDGGDDKENHGECKRPWPQHQCSAPADLGYDGRVDSFTDRTSLSPGSQINVLE
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53969. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ca(2+)/calmodulin-dependent protein kinase phosphatase N; CaMKN; CaMKP-N; CaMKP-nucleus; nuclear calmodulin-dependent protein kinase phosphatase; Partner of PIX 1; Partner of PIX-alpha; Partner of PIXA; PP2C-eta; Protein phosphatase 1E; protein phosphatase 1E (PP2C domain containing); Protein phosphatase 1M; protein phosphatase 1M (PP2C domain containing); protein phosphatase 2C eta-2; Protein phosphatase 2C isoform eta; protein phosphatase, Mg2+/Mn2+ dependent, 1E; protein phosphatase, Mg2+/Mn2+ dependent, 1M
基因别名: CAMKN; CaMKP-N; KIAA1072; POPX1; PP2C-eta; PP2CE; PP2Ceta; PP2CH; PPM1E; PPM1M
UniProt ID: (Human) Q8WY54, (Human) Q96MI6
Entrez Gene ID: (Human) 22843, (Human) 132160
