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Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84064. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
PRDM5, a novel member of PR domain protein family, contains a PR-domain at the -NH2 terminus followed by 16 zinc finger motifs. It is found to have a role in cell differentiation and tumorigenesis. Reports suggest PRDM5 causes G2/M arrest and apoptosis upon infection of tumor cells and has been found to be silenced in breast, ovarian and lung cancers, suggesting a potential clinical significance.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: PR domain containing 5; PR domain zinc finger protein 5; PR domain-containing protein 5
基因别名: BCS2; PFM2; PRDM5
UniProt ID: (Human) Q9NQX1
Entrez Gene ID: (Human) 11107