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产品信息
RP-102820
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
SQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEI
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58319. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
FNBP3, Formin-binding protein 3, is a 957 amino acid protein encoded by the human gene PRPF40A. FNBP3 belongs to the PRPF40 family and contains five FF domains and two WW domains. Nuclear proteins harboring both WW and FF protein interaction modules bind to splicing factors as well as RNA polymerase II and may serve to link transcription with splicing. Through the WW domains, FNBP3 will bind to the Formin proline-rich regions. Also known as Pre-mRNA-processing factor 40 homolog A, FNBP3 binds to WASL/N-WASP (Neuronal Wiskott-Aldrich syndrome protein) complex and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function. FNBP3 is widely expressed in most tissues and is localized to the nuclear speckles.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fas ligand-associated factor 1; Fas-ligand associated factor 1; FLJ20585; formin binding protein 3; Formin-binding protein 11; Formin-binding protein 3; HIP-10; Huntingtin yeast partner A; Huntingtin-interacting protein 10; Huntingtin-interacting protein A; NY-REN-6 antigen; Pre-mRNA-processing factor 40 homolog A; PRP40 pre-mRNA processing factor 40 homolog A; Renal carcinoma antigen NY-REN-6
基因别名: FBP-11; FBP11; FLAF1; FNBP3; HIP-10; HIP10; HSPC225; HYPA; NY-REN-6; Prp40; PRPF40A
UniProt ID: (Human) O75400
Entrez Gene ID: (Human) 55660
