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Highest antigen sequence indentity to the following orthologs: Mouse (36%), Rat (36%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60499. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: deafness 2, perceptive, congenital; deafness, X-linked 2, perceptive, congenital; dJ1070B1.2 (phosphoribosyl pyrophosphate synthetase 1); Phosphoribosyl pyrophosphate synthase I; PPRibP; PRS-I; ribose-phosphate diphosphokinase 1; Ribose-phosphate pyrophosphokinase 1
基因别名: ARTS; CMTX5; DFN2; DFNX1; PPRibP; PRPS1; PRS-I; PRSI
UniProt ID: (Human) P60891
Entrez Gene ID: (Human) 5631