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Highest antigen sequence indentity to the following orthologs: Mouse (30%), Rat (30%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61535. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD112 receptor; CD112R; Poliovirus receptor-related immunoglobulin domain-containing protein; Transmembrane protein PVRIG
基因别名: C7orf15; CD112R; PVRIG
UniProt ID: (Human) Q6DKI7
Entrez Gene ID: (Human) 79037