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Highest antigen sequence indentity to the following orthologs: Mouse (75%), Rat (75%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Bf; C3 Proaccelerator; C3/C5 convertase; cfb; Complement factor P; GBG; H2-Bf; PBF2; Properdin; properdin P factor, complement
基因别名: BFD; CFP; PFC; PFD; PROPERDIN
UniProt ID: (Human) P27918
Entrez Gene ID: (Human) 5199