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产品信息
RP-109111
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
MASPSGSSEATGKPRGRDGRPRREEDDVPPEEKRLRLLLEGGSAEPEDCEDG
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (35%), Rat (35%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A FOX-1; ataxin 2-binding protein 1; Ataxin-2-binding protein 1; Fox-1 homolog A; fox-1-like RNA-binding protein 1; hexaribonucleotide binding protein 1 isoform alpha; hexaribonucleotide binding protein 1 isoform beta; Hexaribonucleotide-binding protein 1; RNA binding protein fox-1 homolog 1; RNA binding protein, fox-1 homolog (C. elegans) 1
基因别名: 2BP1; A2BP; A2BP1; FOX-1; FOX1; HRNBP1; RBFOX1
UniProt ID: (Human) Q9NWB1
Entrez Gene ID: (Human) 54715
