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Highest antigen sequence indentity to the following orthologs: Mouse (99%), Rat (99%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67049. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Catalytic subunit of the DNA polymerase zeta complex, an error-prone polymerase specialized in translesion DNA synthesis (TLS). Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DNA polymerase zeta catalytic subunit; Protein reversionless 3-like; Rev-3, yeast, homolog-like (polymerase, DNA, zeta); REV3-like; REV3-like, polymerase (DNA directed), zeta, catalytic subunit
基因别名: POLZ; REV3; REV3L
UniProt ID: (Human) O60673
Entrez Gene ID: (Human) 5980