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Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56169. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: A1 40 kDa subunit; Activator 1 40 kDa subunit; Activator 1 subunit 2; MGC3665; replication factor C (activator 1) 2, 40kDa; Replication factor C 40 kDa subunit; Replication factor C subunit 2; RF-C 40 kDa subunit
基因别名: RFC2; RFC40
UniProt ID: (Human) P35250
Entrez Gene ID: (Human) 5982