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Highest antigen sequence indentity to the following orthologs: Mouse (73%), Rat (73%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Raft-linking protein 2; Raftlin-2
基因别名: C2orf11; Raftlin-2; RFTN2
UniProt ID: (Human) Q52LD8
Entrez Gene ID: (Human) 130132