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Highest antigen sequence indentity to the following orthologs: Mouse (76%), Rat (76%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62409. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. It may regulate intracellular transport and local transltion of certain mRNAs. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. FXR1 is required for embryonic and postnatal development of muscle tissue. Three transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: RIO kinase 1; Serine/threonine-protein kinase RIO1
基因别名: AD034; bA288G3.1; RIO1; RIOK1; RRP10
UniProt ID: (Human) Q9BRS2
Entrez Gene ID: (Human) 83732