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Retinoid X receptor beta, ligand binding domain (RXRB-LBD) is a 54.5 kDa recombinant human protein (amino acids 295-533) expressed as a GST-tagged fusion protein in insect cells. RXRB-LBD is expressed and purified in the absence of exogenous ligands, making it ideal for ligand binding and coregulator recruitment studies.
Protein Form: Recombinant, Ligand Binding Domain
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DADB-100D22.1; MGC1831; MHC class I promoter binding protein; Nuclear receptor subfamily 2 group B member 2; Retinoic acid receptor RXR-beta; retinoid X receptor; Retinoid X receptor beta; retinoid X receptor, beta; RXR Beta
基因别名: DAUDI6; H-2RIIBP; NR2B2; RCoR-1; RXRB
UniProt ID: (Human) P28702
Entrez Gene ID: (Human) 6257