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产品信息
RP-39310
产品规格
Expression System
E. coli
分类
Recombinant
类型
Protein
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
产品详细信息
This product is a GST-tagged recombinant protein corresponding to full-length human S100 beta.
On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 36kDa.
靶标信息
S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
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