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产品信息
RP-99248
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
KVHRIYRGAGGSFQKAQTEWNTGTWRNPPSREAQYNNFSGNSLPEYPTVPSYPGSGQWP
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60309. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
SCAMPs, or secretory carrier membrane proteins, are membrane proteins that are widely distributed and play a role in membrane trafficking. Most SCAMPs, such as SCAMP1, have N-terminal cytoplasmic NPF repeats, 4 central transmembrane regions, and a short C-terminal cytoplasmic tail. These NPF repeats are likely involved in mediating endocytosis. However, other SCAMPs, like SCAMP4, lack the NPF repeats and are thus unlikely to function in endocytosis. SCAMP4 has been associated with diseases such as Neurodevelopmental Disorder With Brain Abnormalities, Poor Growth, And Dysmorphic Facies and Strabismus.
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生物信息学
蛋白别名: scam4; Secretory carrier membrane protein 4; Secretory carrier-associated membrane protein 4
基因别名: SCAMP-4; SCAMP4
UniProt ID: (Human) Q969E2
Entrez Gene ID: (Human) 113178
