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Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53894. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. May act as coactivator as well as corepressor of E2F1-TFDP1 and E2F4-TFDP1 complexes on E2F consensus binding sites, which would activate or inhibit E2F-target genes expression. Modulates fat storage by down-regulating the expression of key genes involved in adipocyte lipolysis, thermogenesis and oxidative metabolism. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC126688; MGC126690; SERTA domain-containing protein 2; Transcriptional regulator interacting with the PHD-bromodomain 2; transcriptional regulator interacting with the PHS-bromodomain 2; TRIP-Br2
基因别名: KIAA0127; Sei-2; SERTAD2; TRIP-Br2; TRIPBR2
UniProt ID: (Human) Q14140
Entrez Gene ID: (Human) 9792