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Highest antigen sequence indentity to the following orthologs: Mouse (75%), Rat (75%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58059. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a protein with two N-terminal Src homology 3 (SH3) domains and 10 tetratricopeptide repeat (TPR) motifs, and is a member of a small gene family. The gene product has been proposed to be an adapter or docking molecule. Mutations in this gene result in autosomal recessive Charcot-Marie-Tooth disease type 4C, a childhood-onset neurodegenerative disease characterized by demyelination of motor and sensory neurons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: SH3 domain and tetratricopeptide repeat-containing protein 2; SH3 domain and tetratricopeptide repeats-containing protein 2
基因别名: CMT4C; KIAA1985; MNMN; PP12494; SH3TC2
UniProt ID: (Human) Q8TF17
Entrez Gene ID: (Human) 79628